Caspase Activation Inhibits Proteasome Function during Apoptosis
نویسندگان
چکیده
منابع مشابه
Biochemical pathways of caspase activation during apoptosis.
Caspase activation plays a central role in the execution of apoptosis. The key components of the biochemical pathways of caspase activation have been recently elucidated. In this review, we focus on the two most well-studied pathways of caspase activation: the cell surface death receptor pathway and the mitochondria-initiated pathway. In the cell surface death receptor pathway, activation of ca...
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Review on AVEN, with data on DNA/RNA, on the protein encoded and where the gene is implicated.
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Apoptosis, a highly controlled mode of cell death, is utilized to eliminate superfluous, aged, injured or infected cells from the body. Caspases, a family of aspartic acid-specific proteases, are the major effectors of apoptosis. To curtail their activity, caspases are normally synthesized as inactive precursors, but become activated at the onset of apoptosis by activation signals. Once active,...
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ژورنال
عنوان ژورنال: Molecular Cell
سال: 2004
ISSN: 1097-2765
DOI: 10.1016/s1097-2765(04)00156-x